VISUALIZING PHOTODYNAMIC THERAPY IN TRANSGENIC ZEBRAFISH USING ORGANIC NANOPARTICLES WITH AGGREGATION-INDUCED EMISSION

Visualizing Photodynamic Therapy in Transgenic Zebrafish Using Organic Nanoparticles with Aggregation-Induced Emission

Abstract Photodynamic therapy (PDT) employs accumulation of photosensitizers (PSs) in malignant tumor tissue followed by the light-induced generation of cytotoxic reactive oxygen species to kill the tumor cells.The success of PDT depends on optimal PS dosage that is matched with the ideal power of light.This in turn depends on PS accumulation in ta

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Practices of and Perspectives on Palliative Sedation Among Palliative Care Physicians in Ontario, Canada: A Mixed-Methods Study

Background: Palliative sedation (PS) is a therapeutic intervention employed to manage severe and refractory symptoms in terminally ill patients at end of life.Inconsistencies in PS practice guidelines coupled with clinician ambiguity have resulted in confusion about how PS is best integrated into practice.Understanding the perspectives, experiences

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How Impulsivity is Associated with Adolescent Depression: The Role of Substance Use, Gender and Social Support

Tsung-han Lee,1 Hui-Ching Liu,1 Yu-Hsin Huang,1 Fang-Ju Sun,2 Shen-Ing Liu1 1Department of Child and Adolescent Psychiatry, MacKay Memorial Hospital, Taipei City, Taiwan; 2Department of Medical Research, MacKay Memorial Hospital, PRO VISION Taipei City, TaiwanCorrespondence: Shen-Ing Liu, Email maryliuyip@gmail.comBackground: Some risk/protective f

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